Age-related memory impairment is associated with disrupted multivariate epigenetic coordination in the hippocampus.

Mounting evidence linking epigenetic regulation to memory-related synaptic plasticity raises the possibility that altered chromatin modification dynamics might Catheters and Sheaths - Intermittent contribute to age-dependent cognitive decline.Here we show that the coordinated orchestration of both baseline and experience-dependent epigenetic regula

read more


Nrf2 Modulates the Hybrid Epithelial/Mesenchymal Phenotype and Notch Signaling During Collective Cancer Migration

Hybrid epithelial/mesenchymal cells (E/M) are key players in aggressive cancer metastasis.It remains a challenge to understand how these cell states, which are mostly non-existent in healthy tissue, become stable phenotypes participating in collective cancer migration.The transcription factor Boys Hat Nrf2, which is associated with tumor progressio

read more